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Yunnan University
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We report thieno-phospha-rhodamine (TPR) dyes as a novel class of near-infrared (NIR)-emissive fluorophores featuring an unsymmetric π-skeleton. TPR dyes exhibit emission maxima near 800 nm, large Stokes shifts, and excellent photostability. Notably, TPR-Et displays dual organelle localization that dynamically responds to changes in mitochondrial membrane potential and lysosomal pH.


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