Preparation of ZIF-8-based nanocomposites and their notable antibacterial activities†
Abstract
Recent deaths related to antimicrobial resistance have raised alarms for global human health. To overcome this issue, extensive research concentrating on developing novel antibacterial strategies, materials, and methods is needed. In this work, we provide a breakthrough combination of ZIF-8 with silver nanoparticles (Ag NPs), gold NPs (Au NPs), or magnetic iron oxide NPs (Fe3O4 NPs). The obtained nanocomposites were evaluated for essential properties via XRD, UV-vis spectroscopy, FESEM, EDS, VSM, and HRTEM techniques. They also demonstrated remarkable antibacterial activities toward two typical pathogenic bacteria, Escherichia coli and Staphylococcus aureus. Interestingly, the investigated materials' liquid and solid states exhibited superior inhibition zones, with the maximum observed value of 30.7 mm. Thus, our synthesized nanomaterials may show great potential for the application of further strategies in the biomedical field.