Preparation of ZIF-8-based nanocomposites and their notable antibacterial activities

Abstract

Recent deaths related to antimicrobial resistance have raised alarms for global human health. To overcome this issue, extensive research concentrating on developing novel antibacterial strategies, materials, and methods is needed. In this work, we provide a breakthrough combination of ZIF-8 with silver nanoparticles (Ag NPs), gold NPs (Au NPs), or magnetic iron oxide NPs (Fe3O4 NPs). The obtained nanocomposites were evaluated for essential properties via XRD, UV-vis spectroscopy, FESEM, EDS, VSM, and HRTEM techniques. They also demonstrated remarkable antibacterial activities toward two typical pathogenic bacteria, Escherichia coli and Staphylococcus aureus. Interestingly, the investigated materials' liquid and solid states exhibited superior inhibition zones, with the maximum observed value of 30.7 mm. Thus, our synthesized nanomaterials may show great potential for the application of further strategies in the biomedical field.

Graphical abstract: Preparation of ZIF-8-based nanocomposites and their notable antibacterial activities

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Article information

Article type
Paper
Submitted
25 Feb 2025
Accepted
19 Jun 2025
First published
23 Jun 2025
This article is Open Access
Creative Commons BY-NC license

Mater. Adv., 2025, Advance Article

Preparation of ZIF-8-based nanocomposites and their notable antibacterial activities

L. H. Tho, D. T. Anh, H. K. Thi Ta, B. T. Phan, S. Park, S. Kwon, K. T. L. Trinh and N. H. Thi Tran, Mater. Adv., 2025, Advance Article , DOI: 10.1039/D5MA00177C

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