We report the simple synthesis of 1,2-disubstituted benzimidazoles using three versatile building blocks: benzaldehydes, o-phenylenediamines, and phenylpropiolic acid. The protocol facilitates the formation of three C–N bonds and one Csp–Csp bond in a one-pot reaction and yields novel products that have not been previously synthesized.
F. Mohaghegh and F. Jafarpour, Org. Biomol. Chem., 2025, Advance Article , DOI: 10.1039/D5OB00418G
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