From the journal:

Organic & Biomolecular Chemistry

Diastereoselective construction of structurally diverse polycyclic spiroindolenines via Yb(OTf)3-catalyzed cascade [1,5]-hydride transfer/cyclization

Song Hu,   Dan Hu,   Jianming Xu,   Jian Wang,   Heng Yin,   Ying Xie,   Yu-Long Li  and  Chenyi Li  

Abstract

The Lewis acid-catalyzed redox neutral cascade [1, 5]-hydride transfer/cyclization between indolin-2-imines and 2-amino-substituted benzaldehydes has been disclosed. A series of novel pharmaceutically interesting polycyclic spiroindolenines containing tetrahydroquinolines were obtained in good to excellent yields with excellent diastereoselectivities.

About
Cited by
Related
Download options Please wait...

Supplementary files

Transparent peer review

To support increased transparency, we offer authors the option to publish the peer review history alongside their article.

View this article’s peer review history

Article information

DOI
https://doi.org/10.1039/D5OB01005E
Article type
Paper
Submitted
19 Jun 2025
Accepted
28 Jul 2025
First published
29 Jul 2025

Org. Biomol. Chem., 2025, Accepted Manuscript

Permissions

Request permissions

Diastereoselective construction of structurally diverse polycyclic spiroindolenines via Yb(OTf)3-catalyzed cascade [1,5]-hydride transfer/cyclization

S. Hu, D. Hu, J. Xu, J. Wang, H. Yin, Y. Xie, Y. Li and C. Li, Org. Biomol. Chem., 2025, Accepted Manuscript , DOI: 10.1039/D5OB01005E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements